Stuve Lab
The vision of the lab is to further understand the pathogenesis of autoimmunity of the central nervous system through basic science and translational research.
Olaf Stuve, M.D.,Ph.D.
Dr. Olaf Stuve is a tenured Professor in the Department of Neurology at UT Southwestern Medical Center, Head of the MS/ Neuroimmunology section, and Chief of Neurology at the VA North Texas Health Care System/ Dallas VA Medical Center. In addition to his clinical activities, he has been the Principal Investigator and site Principal Investigator for numerous clinical trials. Dr. Stuve also runs a research laboratory at UT Southwestern, which is studying the differential molecular requirements for bone-marrow-derived leukocytes to cross the blood-brain barrier or other biological barriers that provide immune privilege for the central nervous system (CNS). He is also exploring molecular and cellular differences between bone-marrow-derived myeloid cells subsets and CNS-intrinsic microglia, and the potential pathogenic role of innate immune cells in early and late MS. Furthermore, Dr. Stuve's research interests include molecular and cellular markers of autoimmunity, and experimental therapies for autoimmune disorders, and he has numerous ongoing collaborations with national and international investigators.