People

Our Work

The McFadden Lab was established in January 2015 with support from the NCI, Cancer Prevention and Research Institute of Texas (CPRIT), and the UTSW Disease-Oriented Clinical Scholar award.

The lab uses genetic and chemical approaches to identify new therapeutic targets for cancer, including small cell lung cancer, thyroid cancer, and Ewing sarcoma.

Meet the PI

David McFadden, M.D., Ph.D.

David McFadden, M.D., Ph.D.

David is a native Texan and earned his M.D. and Ph.D. degrees at UT Southwestern. He then completed post-graduate medical training at Harvard Medical School (HMS) with an internship and residency in Internal Medicine at Brigham and Women’s Hospital and the Endocrinology Fellowship at the Massachusetts General Hospital (MGH). Following fellowship, he stayed at MGH and HMS as junior faculty and was a member of the Center for Endocrine Tumors and a staff physician in the Thyroid Associates and Endocrine Tumor Genetics clinics.

After completing postdoctoral work at the Massachusetts Institute of Technology, he returned to UT Southwestern as an Assistant Professor of Internal Medicine and Biochemistry in 2015. As a physician, David’s clinical effort lies in the treatment of patients with thyroid cancer, especially those with clinically challenging or advanced disease.  David was elected into the American Society for Clinical Investigation in 2022.

David is an avid sports fan and enjoys spending time with his wife and daughter, fly fishing for striped bass off the coast of Cape Cod, running and various recreational sports, and tasting hoppy ales from around the nation.

Current Lab Members

Tina Vandiver

Lab Manager/Research Assistant

Tina Vandiver

Xin Bai

Staff Scientist

Xin Bai

Juanma Povedano Selfa

Postdoctoral Fellow

Juanma Povedano Selfa

Alex Nguyen

Research Technician

Alex Nguyen

Kelvin Mun

Research Technician

Kelvin Mun

Celia de la Calle Arregui

Postdoctoral Fellow

Celia de la Calle Arregui

Christina Troll

Graduate Student

Christina Troll

Shuai Wang

Staff Scientist

Shuai Wang

Qianqian Zhuang

Postdoctoral Fellow

Qianqian Zhuang

Lab Alumni

Vicky Li

MSTP Student

Vicky Li

James McGinnis

Postdoctoral Fellow

James McGinnis

Anderson Frank

Postdoctoral Fellow - Biggins Lab at Fred Hutch Cancer Center

Anderson Frank

Alberto Bremauntz Enriquez

MSTP Student

Alberto Bremauntz Enriquez

Joel Liou

Research Technician

Joel Liou

Ashwin Srivatsav

UTD Green Fellow

Ashwin Srivatsav

Irene Kim

Research Technician

Irene Kim