Publications

Featured Publications

Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity.
Zhang Z, Funcke JB, Zi Z, Zhao S, Straub LG, Zhu Y, Zhu Q, Crewe C, An YA, Chen S, Li N, Wang MY, Ghaben AL, Lee C, Gautron L, Engelking LJ, Raj P, Deng Y, Gordillo R, Kusminski CM, Scherer PE, Cell Metab 2021 Jun

Interplay between ChREBP and SREBP-1c Coordinates Postprandial Glycolysis and Lipogenesis in Livers of Mice.
Linden AG, Li S, Choi HY, Fang F, Fukasawa M, Uyeda K, Hammer RE, Horton JD, Engelking LJ, Liang G J. Lipid Res. 2018 Jan

Scap is required for sterol synthesis and crypt growth in intestinal mucosa.
McFarlane MR, Cantoria MJ, Linden AG, January BA, Liang G, Engelking LJ J. Lipid Res. 2015 Apr

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin.
Engelking LJ, Evers BM, Richardson JA, Goldstein JL, Brown MS, Liang G J. Clin. Invest. 2006 Sep 116 9 2356-65

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.
Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS J. Clin. Invest. 2005 Sep 115 9 2489-98

Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis.
Engelking LJ, Kuriyama H, Hammer RE, Horton JD, Brown MS, Goldstein JL, Liang G J. Clin. Invest. 2004 Apr 113 8 1168-75