Publications

Development of Intrathecal AAV9 Gene Therapy for Giant Axonal Neuropathy.

Bailey RM, Armao D, Nagabhushan Kalburgi S, Gray SJ 2018 Jun Mol Ther Methods Clin Dev 9 160-171

LRRK2 phosphorylates novel tau epitopes and promotes tauopathy.

Bailey RM, Covy JP, Melrose HL, Rousseau L, Watkinson R, Knight J, Miles S, Farrer MJ, Dickson DW, Giasson BI, Lewis J 2013 Dec Acta Neuropathol. 6 126 809-27

Advancing the pathologic phenotype of giant axonal neuropathy: early involvement of the ocular lens.

Armao D, Bouldin TW, Bailey RM, Hooper JE, Bharucha DX, Gray SJ 2019 02 Orphanet J Rare Dis 1 14 27

Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics.

Bardai FH, Ordonez DG, Bailey RM, Hamm M, Lewis J, Feany MB 2018 Dec PLoS Biol. 12 16 e2006265

Autonomic nervous system involvement in the giant axonal neuropathy (GAN) KO mouse: implications for human disease.

Armao D, Bailey RM, Bouldin TW, Kim Y, Gray SJ 2016 08 Clin. Auton. Res. 4 26 307-13

Physiologically relevant factors influence tau phosphorylation by leucine-rich repeat kinase 2.

Hamm M, Bailey R, Shaw G, Yen SH, Lewis J, Giasson BI 2015 Oct J. Neurosci. Res. 10 93 1567-80

Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model.

Bailey RM, Howard J, Knight J, Sahara N, Dickson DW, Lewis J 2014 Jan Mol Neurodegener 9 8

In vivo functional brain mapping in a conditional mouse model of human tauopathy (tauP301L) reveals reduced neural activity in memory formation structures.

Perez PD, Hall G, Kimura T, Ren Y, Bailey RM, Lewis J, Febo M, Sahara N 2013 Feb Mol Neurodegener 8 9

Neuronal sensitivity to TDP-43 overexpression is dependent on timing of induction.

Cannon A, Yang B, Knight J, Farnham IM, Zhang Y, Wuertzer CA, D'Alton S, Lin WL, Castanedes-Casey M, Rousseau L, Scott B, Jurasic M, Howard J, Yu X, Bailey R, Sarkisian MR, Dickson DW, Petrucelli L, Lewis J 2012 Jun Acta Neuropathol. 6 123 807-23

CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity.

Ko HS, Bailey R, Smith WW, Liu Z, Shin JH, Lee YI, Zhang YJ, Jiang H, Ross CA, Moore DJ, Patterson C, Petrucelli L, Dawson TM, Dawson VL 2009 Feb Proc. Natl. Acad. Sci. U.S.A. 8 106 2897-902

Akt and CHIP coregulate tau degradation through coordinated interactions.

Dickey CA, Koren J, Zhang YJ, Xu YF, Jinwal UK, Birnbaum MJ, Monks B, Sun M, Cheng JQ, Patterson C, Bailey RM, Dunmore J, Soresh S, Leon C, Morgan D, Petrucelli L 2008 Mar Proc. Natl. Acad. Sci. U.S.A. 9 105 3622-7

Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.

Zhang YJ, Xu YF, Dickey CA, Buratti E, Baralle F, Bailey R, Pickering-Brown S, Dickson D, Petrucelli L 2007 Sep J. Neurosci. 39 27 10530-4

Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G.

Vanwert AL, Bailey RM, Sweet DH 2007 Oct Am. J. Physiol. Renal Physiol. 4 293 F1332-41

Identification of potential protein interactors of Lrrk2.

Dächsel JC, Taylor JP, Mok SS, Ross OA, Hinkle KM, Bailey RM, Hines JH, Szutu J, Madden B, Petrucelli L, Farrer MJ 2007 Oct Parkinsonism Relat. Disord. 7 13 382-5

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins.

Dickey CA, Kamal A, Lundgren K, Klosak N, Bailey RM, Dunmore J, Ash P, Shoraka S, Zlatkovic J, Eckman CB, Patterson C, Dickson DW, Nahman NS, Hutton M, Burrows F, Petrucelli L 2007 Mar J. Clin. Invest. 3 117 648-58

The prolyl hydroxylase oxygen-sensing pathway is cytoprotective and allows maintenance of mitochondrial membrane potential during metabolic inhibition.

Sridharan V, Guichard J, Bailey RM, Kasiganesan H, Beeson C, Wright GL 2007 Feb Am. J. Physiol., Cell Physiol. 2 292 C719-28