Cerebellar contribution to autism-relevant behaviors in fragile X syndrome models.
Gibson JM, Vazquez AH, Yamashiro K, Jakkamsetti V, Ren C, Lei K, Dentel B, Pascual JM, Tsai PT, 2023 Dec Cell Rep 12 42 113533Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model.
Dentel B, Angeles-Perez L, Ren C, Jakkamsetti V, Holley AJ, Caballero D, Oh E, Gibson J, Pascual JM, Huber KM, Tu BP, Tsai PT, 2022 May iScience 5 25 104334A critical period for development of cerebellar-mediated autism-relevant social behavior.
Gibson JM, Howland CP, Ren C, Howland C, Vernino A, Tsai PT, 2022 Feb J NeurosciRegulation of autism-relevant behaviors by cerebellar-prefrontal cortical circuits.
Kelly E, Meng F, Fujita H, Morgado F, Kazemi Y, Rice LC, Ren C, Escamilla CO, Gibson JM, Sajadi S, Pendry RJ, Tan T, Ellegood J, Basson MA, Blakely RD, Dindot SV, Golzio C, Hahn MK, Katsanis N, Robins DM, Silverman JL, Singh KK, Wevrick R, Taylor MJ, Hammill C, Anagnostou E, Pfeiffer BE, Stoodley CJ, Lerch JP, du Lac S, Tsai PT, 2020 09 Nat Neurosci 9 23 1102-1110Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors.
Tsai PT, Rudolph S, Guo C, Ellegood J, Gibson JM, Schaeffer SM, Mogavero J, Lerch JP, Regehr W, Sahin M 2018 Oct Cell Rep 2 25 357-367.e4Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M 2012 Aug Nature 7413 488 647-51Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity.
Barone I, Gilette NM, Hawks-Mayer H, Handy J, Zhang KJ, Chifamba FF, Mostafa E, Johnson-Venkatesh EM, Sun Y, Gibson JM, Rotenberg A, Umemori H, Tsai PT, Lipton JO, 2023 Oct Sci Adv 43 9 eadj1010Aberrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy.
Lipton JO, Boyle LM, Yuan ED, Hochstrasser KJ, Chifamba FF, Nathan A, Tsai PT, Davis F, Sahin M 2017 Jul Cell Rep 4 20 868-880Autism and cerebellar dysfunction: Evidence from animal models.
Tsai PT 2016 May Semin Fetal Neonatal MedThe role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders.
Mosconi MW, Wang Z, Schmitt LM, Tsai P, Sweeney JA 2015 Front Neurosci 9 296Cerebellar associative sensory learning defects in five mouse autism models.
Kloth AD, Badura A, Li A, Cherskov A, Connolly SG, Giovannucci A, Bangash MA, Grasselli G, Peñagarikano O, Piochon C, Tsai PT, Geschwind DH, Hansel C, Sahin M, Takumi T, Worley PF, Wang SS 2015 Elife 4Copy number variation plays an important role in clinical epilepsy.
Olson H, Shen Y, Avallone J, Sheidley BR, Pinsky R, Bergin AM, Berry GT, Duffy FH, Eksioglu Y, Harris DJ, Hisama FM, Ho E, Irons M, Jacobsen CM, James P, Kothare S, Khwaja O, Lipton J, Loddenkemper T, Markowitz J, Maski K, Megerian JT, Neilan E, Raffalli PC, Robbins M, Roberts A, Roe E, Rollins C, Sahin M, Sarco D, Schonwald A, Smith SE, Soul J, Stoler JM, Takeoka M, Tan WH, Torres AR, Tsai P, Urion DK, Weissman L, Wolff R, Wu BL, Miller DT, Poduri A 2014 Jun Ann. Neurol. 6 75 943-58Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.
Di Nardo A, Wertz MH, Kwiatkowski E, Tsai PT, Leech JD, Greene-Colozzi E, Goto J, Dilsiz P, Talos DM, Clish CB, Kwiatkowski DJ, Sahin M 2014 Jul Hum. Mol. Genet. 14 23 3865-74Prenatal rapamycin results in early and late behavioral abnormalities in wildtype C57BL/6 mice.
Tsai PT, Greene-Colozzi E, Goto J, Anderl S, Kwiatkowski DJ, Sahin M 2013 Jan Behav. Genet. 1 43 51-9A magnetic resonance imaging study of cerebellar volume in tuberous sclerosis complex.
Weisenfeld NI, Peters JM, Tsai PT, Prabhu SP, Dies KA, Sahin M, Warfield SK 2013 Feb Pediatr. Neurol. 2 48 105-10Cognitive and behavioral characterization of 16p11.2 deletion syndrome.
Hanson E, Nasir RH, Fong A, Lian A, Hundley R, Shen Y, Wu BL, Holm IA, Miller DT 2010 Oct J Dev Behav Pediatr 8 31 649-57A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery.
Tsai PT, Ohab JJ, Kertesz N, Groszer M, Matter C, Gao J, Liu X, Wu H, Carmichael ST 2006 Jan J. Neurosci. 4 26 1269-74BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis.
Tsai PT, Lee RA, Wu H 2003 Dec Blood 12 102 3947-53