Meet the PI

Meet the Principal Investigator

Daniela Nicastro, Ph.D.

Daniela Nicastro, Ph.D.

Associate Professor of Cell Biology and Biophysics

Email

Ph.D. (2000) Ludwig Maximilians University, Munich,Germany

Curriculum Vitae

Education and Positions

1995:  Dipl. Biol. (equivalent of M.S.) in Biology, Ludwig Maximilians University, Munich, Germany

1996-2000: Ph.D. study in Biology, Ludwig Maximilians University and Max Planck Institute for Biochemistry, Munich, Germany

2000-2001: Postdoctoral research in Structural Biology with Dr. Wolfgang Baumeister, MPI for Biochemistry, Munich, Germany

2001-2006: Postdoctoral research in Structural Cell Biology with Dr. Richard J. McIntosh, Univ. of Colorado, Boulder

2006-2013:  Assistant Professor of Biology, Brandeis University, Massachusetts

2013-2015: Associate Professor of Biology, Brandeis University, Massachusetts

2015 July - present: Associate Professor of Cell Biology and Biophysics, UT Southwestern

Honors

1996-1998: Graduate scholarship for Junior Scientists, Ludwig Maximilians University and Bavaria, Germany.

1998-2000: Graduate scholarship, Max Planck Society for the Advancement of Science, Germany.

2000-2001: Postdoctoral scholarship, Max Planck Society, Germany.

2007-2011: Pew Scholar in the Biomedical Sciences

2008: Strage Award for Aspiring Young Science Faculty

2008: WM Keck Foundation Research Excellence Award

2008 - present: LAS (Local Affiliated Societies) tour speaker for the Microscopy Society of America

2009 - 2012: W.M. Keck Foundation Science and Engineering Research Grants Award

2014: Keith R. Porter Fellow

2015: "Rising Star" scholarship from the Cancer Prevention Research Institute of Texas (CPRIT)

2016: Leadership Emerging in Academic Departments (LEAD): 1-year leadership program, capstone project was selected for presentation to the UTSW leadership and has been implemented institutionally. 

2020: WICB Mid-Career Aware for Excellence in Research by the American Society for Cell Biology (ASCB)

2020: Pew Innovation Fund Investigator

Other Experience and Professional Memberships

Editorial Board member: Cytoskeleton

Reviewer of grant proposals: National Science Foundation

Reviewer for journals: Journal of Structural Biology, Journal of Molecular Biology, Nature, PNAS, Cytoskeleton

Membership: American Society for Cell Biology (ASCB), Microscopy Society of America (MSA)

Conference Session Chairs: Tomography Session at the Microscopy and Microanalysis Conference, San Antonio, TX (2003); “Isolated Proteins and Filaments” at the GRC on 3D Electron Microscopy, New London, NH (2007); Tomography Session at the Microscopy and Microanalysis Conference, Ft. Lauderdale, Florida (2007); Mini-symposium on “Molecular Motors: Alone and in Groups” at the 47th Annual Meeting of the ASCB (2007); Tomography session at the GRC on 3D Electron Microscopy, Lucca, Italy (2008); Chair of Tomography Session at the Microscopy and Microanalysis Conference, Phoenix, AZ (2012); Session chair at the 7th International Electron Tomography Conference, Cancun, Mexico (2014); Chair of the Motility Session at the FASEB meeting: “Biology of Cilia”, Snowmass, CO (2015); Chair of the “Motor Assemblies” Session at the GRC meeting: “Muscle and molecular motors”, Mt Snow, VT (2016); Session chair at the Gordon Research Conference on Three Dimensional Electron Microscopy, Diablerets, Switzerland (June 2017); Co-chair of the GRC Connects (Gordon Research Conference) for Three Dimensional Electron Microscopy (Sept. 2020) [virtual meeting due to COVID-19]; Co-chair (2021) of the Gordon Research Conference on Three Dimensional Electron Microscopy, Waterville Valley, NH; Chair of the Gordon Research Conference on Three Dimensional Electron Microscopy, Spain (6/2022); Program Planning Committee for the Protein Society 2023 meeting, Boston, MA

Departmental Seminars: NIAMS/NIH, Bethesda, MD (2000); Zoological Colloquium, Munich, Germany (2000); National Center for Microscopy and Imaging Research, San Diego, CA (2001); Boulder Laboratory for 3-Dimensional Electron Microscopy of Cells, Boulder, CO (2001); Wadsworth Center, Albany, NY (2001); EMBL, Heidelberg, Germany (2003); Brandeis University, Boston, MA (2003); University of California at Berkeley, CA (2004); MRC Laboratory of Molecular Biology, Cambridge, UK (2005); University of Texas Medical School, Houston, TX (2005); University of Texas Medical Branch, Galveston, TX (2005); University of Toronto, Toronto, Canada (2006); Brandeis University, Boston, MA (2006); Boston University, Boston, MA (2007); University of Minnesota, MN (2008);Osborn Lecture at the University of Connecticut Health Center, CT (2008); Rudolf Virchow Center, University of Wuerzburg, Germany (2009); University of Wisconsin – Madison, WI (2009); University of Massachusetts Medical School – Worcester, MA (2010); Rocky Mountain Laboratories/NIAID/NIH, Hamilton, MT (2011); Danforth Plant Science Center, St. Louis, MO (2011); Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (2011); University of Pennsylvania – Philadelphia, PA (2012); Pulmonary Center at Boston University School of Medicine, Boston, MA (2013); Oregon Health & Science University, Portland, OR (2013); University of Vermont, VT (2013); Seminar at HHMI Janelia Farm (2013); Seminar at Purdue, IN (2014); Seminar at University of Pennsylvania – Philadelphia, PA (May 2014); Seminar at University of Texas South Western Medical Center, TX (2014); Seminar at University of Colorado in Boulder; Seminar at University of Georgia, Atlanta, GA (September 2014); Seminar in the Cellular Dynamics seminar series, Harvard, MA (March 2015); Invited speaker at the inaugural symposium of the cryo-EM facility at UTSW (April 2016); Seminar at the Cell Biology Physiology Center at the NIH, Bethesda, MD (May 2016); Invited speaker at the inaugural symposium of the cryo-EM facility at UMass (Oct. 2016); Seminar at University of Illinois, Chicago (January 2017); Seminar at University of Vienna, Austria (June 2017); Seminar at UT Southwestern Medical Center, Microbiology Dept., TX (Sept. 2017); Seminar at the University of Freiburg, Germany (Jan. 2018); Seminar at the ETH Zuerich, Switzerland (Jan. 2018); Seminar at Yale University, New Haven, CT (Oct. 2018); Seminar at the Texas Woman’s University, Biology Department, Denton TX (Nov. 2018); Seminar at UT Southwestern Medical Center, Green Center for Systems Biology, Dallas, TX (Febr. 2019); Seminar at the School of Life Sciences at Tsinghua University, Beijing, China (April 2019); Seminar at the Florida State University, Department of Biological Science, Tallahassee, FL (Febr. 2020); Seminar at the Rosalind Franklin Institute, Harwell, UK (virtual, Oct. 2021); President's Lecture at UT Southwestern (virtual, Oct. 2021); Seminar at University of Massachusetts (virtual, Nov. 2021); Seminar at Harvard Medical School, BCMP Department, Boston, MA (virtual, Nov. 2021); Seminar at Columbia University, New York, NY (virtual, Feb. 2022); Seminar at IGBMC, Illkirch, France (Oct. 2022); Invited David Mitchell Endowed Lecture, SUNY, Upstate Medical University, MY (May 2023)

Instructional activities: IMOD workshop, Boulder, Colorado (2003, 2004); Cryo-EM Workshops at the Scripps Research Institute, La Jolla, California (2003); Guest lecturer at Cold-Spring Harbor Laboratories (2006); Workshop Speaker at the CBS/Imaging Center and MRSEC at the University of Minnesota (2008); EMBO electron tomography workshop in Leiden, Netherlands (2009); Workshop on 3D Solutions in Cryo-Electron Microscopy in Barcelona, Spain (2013)