Role of ubiquitin biology in glycogen metabolism and associated diseases
We research the involvement of ubiquitination in glycogen biology and its role in glycogen metabolism related neurological and neuromuscular diseases. We also aim to develop appropriate therapies against these diseases using cutting-edge technologies such as gene therapy.
Polyglucosans (insoluble glycogen) in the brain of human patient (in red) 
Huge boulder like polyglucosan (insoluble glycogen) inclusions in the muscle 
Polyglucosans (insoluble glycogen) in the muscle of a mouse model 
Autophagic inclusions in the muscle of a mouse model as indicated by the light brown spots 
Myo-macrophagy (macrophage invasion of muscle) as indicated by brown staining 
A ligase-trap strategy to identify substrates of LUBAC components Research
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