Optimizing Therapeutic Strategies Against Lung Cancer Using Multi-Modality Imaging
CPRIT RP200021
Zhang/Liu (Co-PI)
03/01/2020 - 02/28/2023
Goal
To determine the degree to which CycT (cyclopamine tartrate) and HSP2 (heme-sequestering peptide 2) alleviate tumor hypoxia and normalize tumor vasculature
Vascular Image-Guided Optimization of Response (VIGOR) to Therapy in Kidney Cancer
5 R01 CA244579-02
Mason/Pinney (MPI), Role: Co-Investigator
07/01/2020 - 06/30/2025
Goal
To develop the application of a novel vascular disrupting agent (VDA) in combination with leading therapies to enhance the treatment of renal cell carcinoma (RCC) and improve tumor control
Optimizing Therapeutic Strategies Against Lung Cancer Using Multi-Modality Imaging
RP160617
Zhang (PI), Role: Co-PI
03/01/2016 - 02/28/2019
Goals
To investigate whether drugs that target heme synthesis and uptake can be a successful strategy for suppressing lung tumors and improving the effectiveness of chemotherapy by multi-modality imaging