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Core Facilities >

Siegwart Lab

We aim to globally understand how the physical and chemical properties of materials affect interactions with biological systems in the context of improving therapies.

  • Daniel Siegwart, Ph.D.

Sinnett Lab

The Sinnett Lab develops and assesses gene therapies for rare neurodevelopmental disorders.

  • Sarah Sinnett, Ph.D.
Rett syndrome

Smith Lab

The Smith Lab strives to develop enabling tools for organic synthesis, allowing bioactive molecules of great complexity to be prepared in a concise and sustainable fashion.

  • Myles Smith, Ph.D.
Organic Chemistry
Organic Chemistry Biological Chemistry

Solmonson Lab

The Solmonson lab is interested in how the placenta senses and achieves metabolic homeostasis between the adult and fetal compartments during pregnancy. 

  • Ashley Solmonson, Ph.D.
Genetics, Development and Disease

Song Lab

Dr. Song's laboratory focuses on understanding the mechanisms of cell death, including apoptosis, ferroptosis, pH-dependent cell death, and immunogenic cell death.

  • Xinxin Song, M.D., Ph.D.

SoRelle Lab

Our lab aim is to discover and translate findings into diagnostic and therapeutic solutions for patients with allergy.

  • Jeffrey SoRelle, M.D.
molecular diagnostics mast cells allergy IgE Antibody COVID-19 COVID-19 Variants Moleclar Glycosylation Sugar Glycan B cells T cells
Immunology

Sorrell Lab

The Sorrell laboratory utilizes integrative approaches that include metabolomics, transcriptomics, organoid cultures, live microcopy, and animal models, to investigate fundamental pathways that control the uptake of nutrients and the biosynthesis of macromolecules in proliferative cells.

  • Maralice Conacci-Sorrell, Ph.D.
Cancer Biology Cell and Molecular Biology

SRC Center for Translational Research at UTSW

The goal of the Center is to support pre-clinical research that uncovers the mechanisms of pediatric musculoskeletal disorders and explores potential new therapies.

  • Carol Wise, Ph.D.
  • Lawson Copley, M.D.
  • Yinshi Ren, Ph.D.
  • Jonathan Rios, Ph.D.
Genetics, Development and Disease

Sreelatha Lab

Our laboratory is interested in investigating the molecular mechanisms of selenoproteins in health and disease.

  • Anju Sreelatha, Ph.D.
Selenoprotein O
Biological Chemistry Cell and Molecular Biology

Stopschinski Lab

The Stopschinski lab investigates molecular and cellular mechanisms that drive neurodegeneration in Alzheimer’s Disease and other tauopathies with the goal to find new diagnostic and therapeutic approaches for these conditions.

  • Barbara Stopschinski, M.D.

Strand Lab

The main goals of the Strand Lab are to create accurate cellular atlases of the human and mouse lower urinary tract, characterize the molecular and cellular alterations in human lower urinary tract disease, and design new mouse models.

  • Douglas Strand, Ph.D.
Benign prostatic hyperplasia
Cancer Biology Genetics, Development and Disease

Stroud Lab

We investigate epigenome regulation of nervous system development and homeostasis. We are particularly interested in understanding how disruption of these mechanisms lead to neurological disorders.

  • Hume Stroud, Ph.D.

Stuve Lab

The vision of the lab is to further understand the pathogenesis of autoimmunity of the central nervous system through basic science and translational research.

  • Olaf Stuve, M.D., Ph.D.
Immunology

Suleiman Lab

In the Suleiman lab, we focus on studying the podocyte biology, specifically the actin dynamics and cytoskeleton. Our research includes examining the balance of Rac and RhoA, two members of the Rho small GTPases, in both healthy and diseased kidneys. 

  • Hani Suleiman
Glomerular Kidney Diseases Glomerular Basement Membrane Diabetic Nephropathy

Sumer Lab

Sumber Lab conducts translational research that seeks to uncover the mysteries of cancer and develop powerful methods for its detection and cure.

  • Baran Sumer, M.D.
Cell Metabolism Immunology Surgical Imaging
Biomedical Engineering

Sun (Lu) Lab

The Sun Lab studies the most numerous cells in the brain, called “glial cells”.

  • Lu Sun, Ph.D.
neuron-glia interaction oligodendrocytes myelination neuroscience neurological disorders multiple sclerosis neonatal white matter injury
Genetics, Development and Disease Neuroscience

Sun (Matthew) Lab

Our research focuses on developing and testing novel immunotherapies for meningiomas (the most common brain tumors in adults) as well as on understanding the tumor immune microenvironment of meningiomas and other skull base tumors.

  • Matthew Sun

Sun (Xiankai) Lab

The Sun Lab is focused on developing novel imaging probes for noninvasive assessment of specific biomarkers implicated in disease initiation, progression, or regression, and exploring the translational roles of imaging probes and/or methodologies in clinical medicine practice with the ultimate goal to improve the outcome of patient care.

  • Xiankai Sun, Ph.D.
Biomedical Engineering

Syeda Lab

Our lab's focus is to develop novel tools aimed at understanding ion channel physiology and molecular mechanism in an isolated membrane environment.

  • Ruhma Syeda, Ph.D.
Piezo1 Ion channels Mechanotransduction Mechanically activated ion channels Lipid bilayers Single channels Electrophysiology
Molecular Biophysics Neuroscience