Publications

Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence.

Xu L, Pierce JL, Sanchez A, Chen KS, Shukla AA, Fustino NJ, Stuart SH, Bagrodia A, Xiao X, Guo L, Krailo MD, Shaikh F, Billmire DF, Pashankar F, Bestrashniy J, Oosterhuis JW, Gillis AJM, Xie Y, Teot L, Mora J, Poynter JN, Rakheja D, Looijenga LHJ, Draper BW, Frazier AL, Amatruda JF, 2023 May Nat Commun 1 14 2636

Ectopic PLAG1 induces muscular dystrophy in the mouse.

Aguayo JS, Shelton JM, Tan W, Rakheja D, Cai C, Shalaby A, Lee J, Iannaccone ST, Xu L, Chen K, Burns DK, Zheng Y, 2023 Jul Biochem Biophys Res Commun 665 159-168

Pitfalls in the diagnosis of yolk sac tumor: Lessons from a clinical trial.

Yang A, Patterson A, Pavlock T, Chen KS, Gagan J, Hatley ME, Frazier AL, Amatruda JF, Laetsch TW, Rakheja D, 2022 Feb Pediatr Blood Cancer 2 69 e29451

Extrarenal Anaplastic Wilms Tumor: A Case Report With Genomic Analysis And Tumor Models.

Willis KR, Sathe AA, Xing C, Koduru P, Artunduaga M, Butler EB, Park JY, Kurmasheva RT, Houghton PJ, Chen KS, Rakheja D, 2022 Feb J Pediatr Hematol Oncol

Integrated Molecular Analysis Reveals 2 Distinct Subtypes of Pure Seminoma of the Testis.

Medvedev KE, Savelyeva AV, Chen KS, Bagrodia A, Jia L, Grishin NV, 2022 Cancer Inform 21 11769351221132634

Mutations in microRNA processing genes in Wilms tumors derepress the IGF2 regulator PLAG1

Chen KS, Stroup EK, Budhipramono A, Rakheja D, Nichols-Vinueza D, Xu L, Stuart SH, Shukla AA, Fraire C, Mendell JT, Amatruda JF 2018 Jul Genes Dev.

EGF Receptor and mTORC1 are novel therapeutic targets in nonseminomatous germ cell tumors.

Chen KS, Fustino NJ, Shukla AA, Stroup EK, Budhipramono A, Ateek C, Stuart SH, Yamaguchi K, Kapur P, Frazier AL, Lum L, Looijenga LHJ, Laetsch TW, Rakheja D, Amatruda JF 2018 Feb Mol. Cancer Ther.

A novel TP53-KPNA3 translocation defines a de novo treatment-resistant clone in osteosarcoma.

Chen KS, Kwon WS, Kim J, Heo SJ, Kim HS, Kim HK, Kim SH, Lee WS, Chung HC, Rha SY, Hwang TH 2016 Sep Cold Spring Harb Mol Case Stud 5 2 a000992

p53 genes function to restrain mobile elements.

Wylie A, Jones AE, D'Brot A, Lu WJ, Kurtz P, Moran JV, Rakheja D, Chen KS, Hammer RE, Comerford SA, Amatruda JF, Abrams JM 2015 Dec Genes Dev.

Invited reply to amikacin ototoxicity in children with cancer: the problem is the administration schedule.

Chen K, Bach A, Shoup A, Winick N 2014 Feb Pediatr Blood Cancer 2 61 191

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.

Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF 2014 Nat Commun 2 4802

Hearing loss and vestibular dysfunction among children with cancer after receiving aminoglycosides.

Chen KS, Bach A, Shoup A, Winick NJ 2013 Jun Pediatr Blood Cancer

A big catch for germ cell tumour research.

Chen KS, Amatruda JF 2013 Apr PLoS Genet. 4 9 e1003481

DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors.

Amatruda JF, Ross JA, Christensen B, Fustino NJ, Chen KS, Hooten AJ, Nelson H, Kuriger JK, Rakheja D, Frazier AL, Poynter JN 2013 BMC Cancer 1 13 313

Hemolytic non-uremic syndrome.

Chen KS, Neunert CE, Crary SE, Buchanan GR 2012 Jul Pediatr Blood Cancer 1 59 167-9

A large T cell invagination with CD2 enrichment resets receptor engagement in the immunological synapse.

Singleton K, Parvaze N, Dama KR, Chen KS, Jennings P, Purtic B, Sjaastad MD, Gilpin C, Davis MM, Wülfing C 2006 Oct J. Immunol. 7 177 4402-13

Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset.

Cooper MA, Fehniger TA, Turner SC, Chen KS, Ghaheri BA, Ghayur T, Carson WE, Caligiuri MA 2001 May Blood 10 97 3146-51