Obesity and metabolic diseases have been increasing at the alarming rate and threatening our health and economy over the world. However, we still don’t know much about how our metabolic homeostasis is regulated. Understanding the mechanism underlying the regulation of metabolism is a fundamental step towards designing new treatments for obesity and its associated diseases, and many other metabolic diseases
We are interested in the circuit mechanisms of how the cerebellum helps the brain to work better in health and disease.
Our lab is studying novel regulatory mechanisms that control innate immunity in intestinal health and disease.
Our research is driven by a desire to understand how these microscopic machines both replicate themselves and, at the same time, manage to evade, manipulate, and counter a myriad of host defenses.
We are working at the interface of nanotechnology, drug delivery, and tumor immunology
Our laboratory aims to understand the role of metabolic adaptive mechanisms in cancer progression.
Dr. Garg's research focuses on diabetes, insulin resistance, and disorders of adipose tissue.
The autonomic nervous system comprises a network of sensory and motor neurons that connect the brainstem and spinal cord to thoracic and abdominal organs. A better understanding of the anatomical and functional plasticity of the autonomic nervous system will likely move forward our understanding of numerous chronic diseases including, but not limited to, obesity, diabetes, visceral pain, neuropathy, and eating disorders.
We seek breakthroughs that change scientific fields and yield new strategies for treating disease. Our ultimate goal is to cure people who would not be cured otherwise.
The German Lab focuses its research on Neurodegenerative Diseases and Autism.
Dr. Gibson's current research focuses on the changes in neocortical circuitry in the mouse model of Fragile X Syndrome (the Fmr1 KO mouse), and the mechanisms underlying these changes.
The Gill lab studies the molecular and metabolic pathways that influence melanoma progression and metastasis.
The Glass lab focuses on how genes regulate skin development and function by studying how gene mutations or abnormal gene expression lead to skin disease.
Goldsmith Lab combines drug discovery and mechanistic analysis to understanding protein kinases.
The Gospocic group studies how epigenetic pathways and gene expression regulate brain plasticity in the context of social behavior and aging by working with a unique ant species Harpegnathos saltator. We take a multidisciplinary approach and combine functional genomics, biochemistry, and behavioral assays in H. saltator, as well as the conventional Drosophila and mouse models to expedite genetic screening and provide evolutionary context to identified epigenetic pathways.
Specialty Areas: epigenetics, chromatin biology, gene regulation, social behavior, aging, neurodegeneration
The Goss lab collaborates with a multidisciplinary group of researchers to study the heart and lungs long after preterm birth. We are part of the Parkland Outcomes after Prematurity Study (POPS), which conducts collaborative research on outcomes of prematurity from birth through adulthood.
Dr. Gray is overseeing one of the nation’s few facilities that manufactures a special type of gene-delivering virus for patient use.
The general focus of the Green Lab is to understand the molecular mechanism of the mammalian circadian clock, how it controls rhythmic biochemistry, physiology and behavior and how loss of clock function can impact health, resulting in metabolic disease, cancer and other ailments.
The Greenberg Lab focuses on translational research relative to autoimmune disorders of the central nervous system.
The Greenberg lab is focused on the development of novel therapeutic approaches to combat infectious diseases. For specific projects, please click on the links to the left.
Our lab uses a combination of electrophysiological and molecular techniques to examine functions sub-served by these states at the cellular and circuit levels.
Working at the boundary between science and philosophy with the goal to inform public policy and advance science education and public understanding of science.
We use theoretical methods to study proteins, genomes and organisms.
The Grow lab takes genome-wide, single-cell, and computational approaches to deeply understand epigenome and transcriptome landscapes and how they are reprogrammed.
Our goal is to tackle difficult problems in human health and cancer biology. We work on the diseases of triple-negative breast cancer and other difficult-to-treat cancers.
